A. Catharine Ross, Ph.D.

photo of A. Ross

Dorothy Foehr Chair and Professor

Contact Information

204 Chandlee Laboratory
The Pennsylvania State University
University Park PA 16802

814-865-4721

(fax) 814-865-4723

acr6@psu.edu

Education

Ph.D., Cornell University, 1976

Research Interests

Vitamin A/retinoid metabolism

Hepatic retinoid function and gene expression

Vitamin A in infection and immunity

Vitamin A and lung development in neonatal period

Selected Publications

Owusu SA, Ross AC. Retinoid homeostatic gene expression in liver, lung and kidney: ontogeny and response to vitamin A-retinoic acid (VARA) supplementation from birth to adult age. PLOS One, 11(1):e0145924, 2016.

Hao L, Huang K-H, Ito K, Sae-tan S, Lambert JD, Ross AC. Fibroblast Growth Factor (FGF)-21 gene expression is elevated in the liver of mice fed a high-carbohydrate liquid diet and attenuated by lipid emulsion, but is not upregulated in liver of mice fed a high-fat obesogenic diet. J Nutr. 146(2): 184-90, 2016.

Tan L, Babbs AE, Green MH, Ross AC. Direct and indirect vitamin A supplementation strategies result in different plasma and tissue retinol kinetics in neonatal rats. J. Lipid Res. 57(8):1423-1434, 2016.

Hodges JK, Tan L, Green MH, Ross AC. Vitamin A supplementation increases the uptake of chylomicron retinyl esters into the brain of neonatal rats raised under vitamin A-marginal conditions. J. Nutr. 146(9):1677-1683, 2016.

Hodges JK, Tan L, Green MH, Ross AC. Vitamin A supplementation transiently increases retinol concentrations in extrahepatic organs of neonatal rats raised under vitamin A-marginal conditions. J. Nutr. 146(10)1953-1960, 2016.

Tan L, Wray AE, Green MH, Ross AC, Retinol kinetics in unsupplemented and vitamin A-retinoic acid supplemented neonatal rats: A preliminary model. J. Lipid Res. 55:1738-1749, 2014.

Zolfaghari R, Ross AC. Hepatocyte nuclear factor 4α (HNF4α) in coordination with retinoic acid receptors increases CYP26A1 expression in hepatocytes. J. Cell. Biochem. E-pub May 12, 2014.

Tan LT, Wray AE, Green MH, Ross AC, Compartmental modeling of whole-body vitamin A kinetics in unsupplemented and vitamin A-retinoic acid supplemented neonatal rats. J Lipid Res 55:1077-1086, 2014.

Hao L, Ito K, Huang K-H, Sae-tan, S, Lambert JD, Ross AC.. Shifts in dietary carbohydrate-lipid exposure regulate expression of the non-alcoholic fatty liver disease-associated gene PNPLA3/adiponutrin in mouse liver and HepG2 human liver cells. Metabolism E-pub Jun 21, 2014.

Ito K, Hao L, Wray AE, Ross AC. Lipid emulsion administered intravenously or orally attenuates triglyceride accumulation and expression of inflammatory markers in the liver of nonobese mice fed parenteral nutrition formula, J. Nutr. 143:253-259, 2013.

Courses Taught

NUTR 490W Nutrition Seminar

NUTR 502 Regulation of Nutrient Metabolism II (Vitamins section)

NUTR 508 Readings in Molecular Nutrition

NUTR 583 Nutritional Epidemiology

Strategic Themes

  • Domains of Health and Behavior